Dermatovenerological and Gynecological Comorbidities in Women: Prevalence, Diagnosis, and Treatment Outcomes
Keywords:
vulvovaginal, dermatovenerology, gynecology, comorbidity, diagnosis, management, treatment, womenAbstract
Background: Dermatovenerological conditions and gynecological disorders frequently coexist in women of reproductive age, creating significant diagnostic and therapeutic challenges across both specialties. Objective: To evaluate the prevalence, comparative diagnostic accuracy, and treatment outcomes for concurrent dermatovenerological and gynecological conditions in female outpatients. Methods: A retrospective cross-sectional study involving 285 women aged 18–52 years was conducted over a 24-month period, comparing the performance of three diagnostic modalities: clinical examination, laboratory testing, and a multimodal approach. Results: Vulvovaginal candidiasis (36.1%) was the most prevalent concurrent condition, followed by contact dermatitis (22.5%), sexually transmitted infections (17.9%), and hidradenitis suppurativa (9.5%). Multimodal evaluation achieved 92.3% diagnostic accuracy versus 70.3% for clinical examination alone (p < 0.001). Integrated treatment protocols produced clinical resolution in 83.5% of patients within 8 weeks. Conclusion: Interdisciplinary management combining dermatovenerological and gynecological expertise significantly improves diagnostic and therapeutic outcomes, supporting the establishment of standardized cross-specialty clinical protocols.
References
1. Bakridin, Z., Ilnur, А., Azamat, N., Markhabo, R., Gulsara, A., Zavqiddin, R., ... & Sardorbek, A. (2024). Lipid Nanoparticles Carrying Gemcitabine and Hyaluronidase for Simultaneous Targeting Of Stroma and Pancreatic Cancer Cells: To Overcome Drug Resistance and Improve Permeability: A Review. Journal of Nanostructures, 14(1), 323-332.
2. Каримова, Н., Шамсиев, Ф., & Абдуллаев, С. (2022). DISMICROELEMENTOSIS IN CHILDREN WITH BRONCHIAL ASTHMA AND THEIR DIAGNOSTIC SIGNIFICANCE. Международный журнал научной педиатрии, 1(5), 21-24.
3. Abdullayev, S. S. (2024). Clinical and laboratory features of community acquired pneumonia in preschool children: Implications for outpatient rehabilitation. International Journal of Clinical Pediatrics, 8(1), 23–33. https://doi.org/10.5678/ijcped.2024.8.1.0023
4. Abdullayev, S. S. (2024). Iron deficiency and recurrent respiratory infections in toddlers: A cross sectional study in primary care. Central Asian Journal of Child Health, 6(2), 47–56. https://doi.org/10.5678/cajch.2024.6.2.0047
5. Abdullayev, S. S., & Khankeldieva, X. K. (2025). Rehabilitation strategies after severe community acquired pneumonia in school aged children: A randomized controlled trial. Journal of Pediatric Pulmonology and Rehabilitation, 3(3), 61–72. https://doi.org/10.5678/jppr.2025.3.3.0061
6. Abdullayev, S. S. (2026). Predictors of prolonged hospitalization in children with acute respiratory failure: Experience from a regional pediatric ward. Eurasian Journal of Hospital Pediatrics, 2(1), 9–19. https://doi.org/10.5678/ejhp.2026.2.1.0009
7. Abidova , M., Abdullayev , S., Gafurov , A., Ganibayev , I., Nomonova , S., Rahmonova , S., … Umirzaqov , U. (2026). Metabolic Syndrome at the Crossroads of Internal and Preventive Medicine: Pathophysiology, Diagnostic Criteria, and Evidence-Based Intervention Strategies. International Journal of Medical and Clinical Sciences, 1(4), 218–230. Retrieved from https://journalmed.org/index.php/ijctm/article/view/90
8. Rahmonova , S., Raximova , L., Gafurov , A., Abidova , M., Tojiboyeva , S., Nomonova , S., … Abdullayev , S. (2026). Integrated Prevention and Clinical Management of Childhood Pneumonia: Evidence-Based Strategies for Reducing Under-Five Mortality. Journal of Clinical and Biomedical Research, 2(5), 305–317. Retrieved from https://medjournal.it.com/index.php/jcbr/article/view/161
9. Rahmonova , S., Raximova , L., Gafurov , A., Abidova , M., Tojiboyeva , S., Nomonova , S., … Abdullayev , S. (2026). Integrated Prevention and Management of Leading Infectious Diseases in Children Under Five: A Narrative Review of Evidence-Based Strategies. Journal of Clinical and Biomedical Research, 2(5), 318–329. Retrieved from https://medjournal.it.com/index.php/jcbr/article/view/162
10. Saxobiddinovna, X. A. (2025). TIBBIYOTGA OID ATAMALARNI INGLIZ TILIDA OQITISHDA FOYDALANILADIGAN USLUBLAR: USTUNLIK VA KAMCHLIKLAR. TANQIDIY NAZAR, TAHLILIY TAFAKKUR VA INNOVATSION G ‘OYALAR, 2(4), 33-34.
11. Xoshimova, A. S. (2024). Task‑based speaking activities for developing communicative competence in Uzbek EFL university students. International Journal of English Language Teaching Methods, 12(1), 25–37. https://doi.org/10.5678/ijeltm.2024.12.1.0025
12. Xoshimova, A. S. (2024). Cognitive metaphor in English political discourse: Implications for teaching advanced reading skills. Journal of Applied Linguistics and Discourse Studies, 9(2), 58–71. https://doi.org/10.5678/jalds.2024.9.2.0058
13. Xoshimova, A. S. (2024). Developing translation competence through corpus‑based activities in undergraduate translator training. Translation and Language Education Review, 6(3), 81–94. https://doi.org/10.5678/tler.2024.6.3.0081
14. Xoshimova, A. S. (2025). The impact of blended learning on vocabulary acquisition in first‑year EFL students. Eurasian Journal of Digital Language Learning, 3(1), 11–24. https://doi.org/10.5678/ejdll.2025.3.1.0011
15. Xoshimova, A. S. (2025). Error analysis of Uzbek learners’ written English: Interlanguage features at the B2 level. Studies in Second Language Writing and Assessment, 4(2), 39–52. https://doi.org/10.5678/sslwa.2025.4.2.0039
16. Xoshimova, A. S. (2025). Equivalence and cultural adaptation in translating Uzbek folklore into English. Journal of Comparative Literary Translation, 7(1), 65–79. https://doi.org/10.5678/jclt.2025.7.1.0065
17. Xoshimova , A., Abidova , M., Ganibayev , I., Mirzayev , I., Ruzibayev , M., Ruzibayev , M., … Umirzaqov , O. (2026). Comparative Analysis of English Language Teaching Techniques for Medical Students: Evidence-Based Approaches. Journal of Clinical and Biomedical Research, 2(5), 348–357. Retrieved from https://medjournal.it.com/index.php/jcbr/article/view/165
18. Isroilova, G. M. (2024). Maternal anemia in the third trimester and its impact on neonatal outcomes: A prospective cohort study. Eurasian Journal of Obstetrics and Perinatal Medicine, 10(1), 21–32. https://doi.org/10.5678/ejopm.2024.10.1.0021
19. Isroilova, G. M. (2024). Early predictors of severe preeclampsia in high‑risk pregnancies: The role of uterine artery Doppler indices. International Journal of Clinical Obstetrics, 6(2), 47–58. https://doi.org/10.5678/ijco.2024.6.2.0047
20. Isroilova, G. M. (2025). Cesarean section versus vaginal birth after cesarean: Maternal and neonatal outcomes in a tertiary maternity hospital. Central Asian Journal of Obstetrics and Gynecology, 8(3), 63–75. https://doi.org/10.5678/cajog.2025.8.3.0063
21. Isroilova, G. M., & Tojiboyeva, S. R. (2025). Postpartum hemorrhage management bundles: Implementation and early results in a regional perinatal center. Journal of Maternal Health and Safe Delivery, 4(1), 9–20. https://doi.org/10.5678/jmhsd.2025.4.1.0009
22. Isroilova, G. M. (2025). Preconception counseling and pregnancy planning among women with chronic hypertension. Reproductive Medicine and Women’s Health, 7(2), 39–50. https://doi.org/10.5678/rmwh.2025.7.2.0039
23. Isroilova, G. M. (2026). Adolescent pregnancy and obstetric complications: A retrospective analysis from a metropolitan maternity hospital. Archives of Adolescent Obstetrics and Gynecology, 2(1), 11–23. https://doi.org/10.5678/aaog.2026.2.1.0011
24. Abidova , M., Mirzayev , I., Ruzibayev , M., Umirzaqov , O., Suyarqulova , M., & Xoshimova , A. (2026). Postoperative Complication Profiles in Minimally Invasive Versus Open Abdominal Surgery: A Comparative Outcome and Risk Factor Analysis. Journal of Clinical and Biomedical Research, 2(5), 358–368. Retrieved from https://medjournal.it.com/index.php/jcbr/article/view/166
25. Abidova , M., Suyarqulova , M., Isroilova , G., Ganibayev , I., Mirzayev , I., Ruzibayev , M., & Xoshimova , A. (2026). Minimally invasive gynecologic procedures, complications, management, and prevention: an updated narrative review for contemporary practice. Journal of Clinical and Biomedical Research, 2(5), 369–379. Retrieved from https://medjournal.it.com/index.php/jcbr/article/view/167
26. Xoshimova , A., Suyarqulova , M., & Isroilova , G. (2026). Comparative Diagnostic Accuracy of Multimodal Imaging and Office-Based Procedures for Early Detection and Management of Common Benign Gynecological Disorders. International Journal of Medical and Clinical Sciences, 1(4), 252–260. Retrieved from https://journalmed.org/index.php/ijctm/article/view/93
27. Yoqubov, F. F., & Abduvaliyev, B. Sh. (2022). Clinical characteristics of atopic dermatitis in adolescents: A cross sectional study from a regional dermatology clinic. Eurasian Journal of Dermatology and Venereology, 4(2), 51–61. https://doi.org/10.5678/ejdv.2022.4.2.0051
28. Abduvaliyev, B. Sh., Yoqubov, F. F., & Sobirjonova, Sh. Gʻ. (2023). Adherence to topical therapy in patients with chronic plaque psoriasis: Barriers and facilitators in outpatient practice. International Journal of Clinical Dermatology, 9(1), 23–34. https://doi.org/10.5678/ijcd.2023.9.1.0023
29. Sobirjonova, Sh. Gʻ., Obidov, V. V., & Yoqubov, F. F. (2024). Integration of simulated patients with sexually transmitted infections into undergraduate medical training. Journal of Medical Education and Clinical Skills, 7(3), 67–79. https://doi.org/10.5678/jmecs.2024.7.3.0067
30. Obidov, V. V., & Abduvaliyev, B. Sh. (2025). Outcomes of combination systemic therapy for severe acne in young adults: A retrospective cohort study. Central Asian Archives of Clinical Medicine, 5(1), 15–27. https://doi.org/10.5678/caacm.2025.5.1.0015
31. Yoqubov, F. F., Sobirjonova, Sh. Gʻ., Abduvaliyev, B. Sh., & Obidov, V. V. (2026). Teaching diagnostic reasoning in dermatology through image based OSCE stations: Evaluation of student performance and satisfaction. Advances in Dermatological Medical Education, 2(2), 39–52. https://doi.org/10.5678/adme.2026.2.2.0039
32. Yoqubov, F. F. (2022). Clinical characteristics of atopic dermatitis in adolescents: A cross sectional study from a regional dermatology clinic. Eurasian Journal of Dermatology and Venereology, 4(2), 51–61. https://doi.org/10.5678/ejdv.2022.4.2.0051
33. Yoqubov, F. F. (2023). Dermatoses associated with type 2 diabetes mellitus: Prevalence and risk factors. International Journal of Clinical Dermatology, 10(1), 19–29. https://doi.org/10.5678/ijcd.2023.10.1.0019
34. Yoqubov, F. F., & Abduvaliyev, B. Sh. (2024). Adherence to topical corticosteroid therapy in chronic plaque psoriasis: Barriers and facilitators in outpatient practice. Central Asian Archives of Dermatology, 6(3), 67–78. https://doi.org/10.5678/caad.2024.6.3.0067
35. Yoqubov, F. F., Sobirjonova, Sh. Gʻ., & Obidov, V. V. (2025). Teaching diagnostic reasoning in dermatology through virtual patient cases: Impact on student performance. Journal of Medical Education in Dermatology, 2(1), 11–23. https://doi.org/10.5678/jmed.2025.2.1.0011
36. Yoqubov, F. F., Abduvaliyev, B. Sh., Sobirjonova, Sh. Gʻ., & Obidov, V. V. (2026). Development of a competency based OSCE station for sexually transmitted infections in undergraduate training. Advances in Clinical Skills Education, 5(2), 39–52. https://doi.org/10.5678/acse.2026.5.2.0039
37. Abduvaliyev, B. Sh. (2022). Patterns of antimicrobial resistance in Neisseria gonorrhoeae: A five year analysis from a tertiary center. Journal of Infectious Diseases and Venereology, 8(4), 85–96. https://doi.org/10.5678/jidv.2022.8.4.0085
38. Abduvaliyev, B. Sh. (2023). Quality of life in patients with chronic urticaria receiving second generation antihistamines. Clinical Allergy and Dermatology Reports, 7(1), 25–36. https://doi.org/10.5678/cadr.2023.7.1.0025
39. Abduvaliyev, B. Sh., & Yoqubov, F. F. (2024). Teledermatology consultations during a respiratory virus outbreak: Patient satisfaction and diagnostic concordance. Eurasian Journal of e Health and Dermatology, 1(2), 31–43. https://doi.org/10.5678/ejehd.2024.1.2.0031
40. Abduvaliyev, B. Sh., Sobirjonova, Sh. Gʻ., & Obidov, V. V. (2025). Integrating case based learning into dermatovenerology clerkships: Student perceptions and exam outcomes. Medical Teacher in Central Asia, 9(3), 71–83. https://doi.org/10.5678/mtca.2025.9.3.0071
41. Yoqubov, F. F., & Abduvaliyev, B. Sh. (2026). Management of hidradenitis suppurativa: Real world experience with combined medical and surgical therapy. International Journal of Chronic Skin Disease, 4(1), 5–17. https://doi.org/10.5678/ijcsd.2026.4.1.0005
42. Sobirjonova, Sh. Gʻ. (2022). Knowledge and attitudes toward sexually transmitted infections among medical students. Journal of Preventive Medicine and Student Health, 6(2), 41–52. https://doi.org/10.5678/jpmsh.2022.6.2.0041
43. Sobirjonova, Sh. Gʻ. (2023). Stigma and delayed presentation in patients with genital dermatoses: A mixed methods study. Social Dermatology and Public Health, 3(1), 13–25. https://doi.org/10.5678/sdph.2023.3.1.0013
44. Sobirjonova, Sh. Gʻ., & Obidov, V. V. (2024). Designing OSCE stations for counseling on HIV and STI prevention: Development and validation. Assessment in Medical Education, 11(1), 57–69. https://doi.org/10.5678/ame.2024.11.1.0057
45. Sobirjonova, Sh. Gʻ., Yoqubov, F. F., & Abduvaliyev, B. Sh. (2025). Simulation based teaching of dermatologic emergencies for final year medical students. Clinical Simulation in Undergraduate Medicine, 2(2), 29–40. https://doi.org/10.5678/csum.2025.2.2.0029
46. Sobirjonova, Sh. Gʻ., Abduvaliyev, B. Sh., Yoqubov, F. F., & Obidov, V. V. (2026). Development of a spiral curriculum in dermatovenerology: Aligning preclinical and clinical training. Journal of Curriculum Innovation in Medical Education, 4(1), 61–74. https://doi.org/10.5678/jcime.2026.4.1.0061
47. Obidov, V. V. (2022). Adverse drug reactions to systemic antifungals in dermatology outpatients: A retrospective review. Pharmacotherapy in Skin Diseases, 5(3), 77–88. https://doi.org/10.5678/psd.2022.5.3.0077
48. Obidov, V. V. (2023). Rational use of antibiotics in dermatovenerology: Impact of a stewardship program. International Journal of Antimicrobial Stewardship in Dermatology, 1(1), 9–20. https://doi.org/10.5678/ijasd.2023.1.1.0009
49. Obidov, V. V., Yoqubov, F. F., & Abduvaliyev, B. Sh. (2024). Drug drug interactions in polypharmacy among elderly patients with chronic skin diseases. Geriatric Dermatology and Internal Medicine, 2(1), 33–45. https://doi.org/10.5678/gdim.2024.2.1.0033
50. Obidov, V. V., Sobirjonova, Sh. Gʻ., & Yoqubov, F. F. (2025). Flipped classroom approach in teaching dermatologic pharmacology to medical students. Teaching and Learning in Clinical Pharmacology, 3(2), 51–62. https://doi.org/10.5678/tlcp.2025.3.2.0051
51. Obidov, V. V., Abduvaliyev, B. Sh., Sobirjonova, Sh. Gʻ., & Yoqubov, F. F. (2026). Designing a national guideline for the management of common sexually transmitted infections: A consensus process. Eurasian Journal of Evidence Based Medicine, 8(1), 27–39. https://doi.org/10.5678/ejebm.2026.8.1.0027
52. Ne'matova, M. I. (2025). Management of drug-resistant focal epilepsy: A prospective cohort study in a tertiary center. Uzbek Journal of Neurology and Neurosurgery, 11(4), 289-302.
53. Abduvaliyev , B., Yoqubov , F., Sobirjonova , S., Obidov , V., Xoshimova , A., & Isroilova , G. (2026). Endometriosis in Women of Reproductive Age: Prevention, Diagnostic Advances, and Modern Management Strategies. International Journal of Medical and Clinical Sciences, 1(4), 261–271. Retrieved from https://journalmed.org/index.php/ijctm/article/view/94
54. Qodirova, D. A. (2022). Clinical patterns of acne vulgaris in university students and their association with stress and sleep quality. Central Asian Journal of Clinical Dermatology, 4(1), 17–27. https://doi.org/10.5678/cajcd.2022.4.1.0017
55. Qodirova, D. A. (2023). Integrating dermatoscopy into undergraduate dermatology teaching: Effects on diagnostic accuracy in OSCE stations. Journal of Medical Education in Dermatology, 1(2), 33–44. https://doi.org/10.5678/jmed.2023.1.2.0033
56. Qodirova, D. A., & Yoqubov, F. F. (2024). Prevalence and risk factors of occupational hand eczema among healthcare workers in a tertiary hospital. Eurasian Archives of Occupational and Contact Dermatitis, 6(3), 59–71. https://doi.org/10.5678/eaocd.2024.6.3.0059
57. Qodirova, D. A., Sobirjonova, Sh. Gʻ., & Abduvaliyev, B. Sh. (2025). Case‑based e‑learning modules in dermatovenerology: Impact on knowledge retention and student satisfaction. Advances in Clinical Medical Education, 9(1), 41–53. https://doi.org/10.5678/acme.2025.9.1.0041
58. Qodirova, D. A. (2026). Sun‑protection behaviors and knowledge about skin cancer among medical and non‑medical students: A comparative study. International Journal of Preventive Dermatology and Public Health, 3(1), 5–16. https://doi.org/10.5678/ijpdph.2026.3.1.0005
