International Journal of Medical and Clinical Sciences

The June 2026 issue of the International Journal of Clinical & Translational Medicine (IJCTM) brings together a curated selection of high-impact studies spanning oncology, infectious disease, critical care, pediatrics, and the rapidly evolving field of artificial intelligence in medicine. This issue reflects the journal's core mission: to accelerate the translation of scientific discovery into meaningful clinical practice.

Among the highlights, this issue features a multi-center cohort study examining gut microbiome signatures in early-stage colorectal cancer, and a systematic review with meta-analysis evaluating machine learning-based early warning systems for sepsis — both of which address urgent priorities in global health. A randomized controlled trial on probiotic supplementation in pediatric antibiotic-associated diarrhea further underscores our commitment to evidence-based therapeutic decision-making in vulnerable populations.

Translational contributions include a CRISPR-based diagnostic platform for rapid detection of drug-resistant tuberculosis, alongside a biomarker panel study for acute kidney injury prediction in critically ill patients. A comprehensive meta-analysis of telehealth interventions across 48 randomized trials offers timely evidence for digital health policy, while a case series documents novel pediatric presentations of autoimmune hepatitis.

This issue closes with a thought-provoking Perspectives piece examining the translational gaps and implementation challenges facing artificial intelligence in clinical radiology — a fitting reflection on both the promise and the responsibility that defines modern translational medicine.

IJCTM remains fully open access under the CC BY 4.0 license. All articles underwent rigorous double-blind peer review prior to publication.