Artificial Intelligence–Driven Radiomics in Otorhinolaryngology: Enhancing Diagnosis and Outcome Prediction in Head and Neck Cancer
Keywords:
artificial intelligence, radiomics, head and neck cancer, machine learning, outcome prediction, otorhinolaryngology, imagingAbstract
Recent advances in otorhinolaryngology have shifted toward data‑driven, imaging‑centric paradigms, with artificial intelligence (AI)‑integrated radiomics playing an increasingly central role in head and neck cancer management. AI‑based radiomics models extract quantitative features from computed tomography, magnetic resonance imaging, and positron‑emission tomography datasets to support noninvasive tumor characterization, treatment planning, and outcome prediction. This article reviews the integration of machine learning and deep‑learning radiomics into routine otolaryngology practice, compares conventional radiomics with emerging end‑to‑end deep‑learning approaches, and discusses practical implementation challenges and future directions. Data from recent studies indicate that combined clinical–radiomic models can improve prediction of survival, recurrence, and treatment response, while preserving or even surpassing the performance of conventional staging alone.
References
1. Melibayeva, F. A., & Axmadaliyeva, G. (2026). AI Driven Analysis of Postoperative Complications: Transforming Surgical Outcomes Through Predictive, Text Based, and Wound Imaging Tools. Journal of Clinical and Biomedical Research, 2(1), 216-222.
2. Melibayeva, F. A., & Axmadaliyeva, G. (2026). AI Enhanced Early Detection of Postoperative Complications: Comparing Traditional, Machine Learning, and Deep Learning Surveillance Models. Journal of Clinical and Biomedical Research, 2(1), 223-230.
3. Meliboyeva, F. A., & Axmadaliyeva, G. (2026). Advancing Diagnostic Skills in Medical Students: A Comparative Analysis of Simulation Based Learning, PBL, DICL, and Case Based Approaches. International Journal of Clinical & Translational Medicine, 1(1), 93-98.
4. Meliboyeva, F. A., & Axmadaliyeva, G. (2026). Beyond Black-Box Algorithms: Artificial Intelligence for Enhancing Diagnostic Tactics in Clinical Care. International Journal of Clinical & Translational Medicine, 1(1), 68-75.
5. Meliboyeva, F. A., & Axmadaliyeva, G. (2026). Integrating Virtual Simulation Into Pediatric Medical Education: Opportunities and Challenges. International Journal of Clinical & Translational Medicine, 1(1), 76-83.
6. Meliboyeva, F. A., & Axmadaliyeva, G. (2026). Terminology as a Clinical Language: A Deep Review of Core Medical Terms and Their Subject Specific Usage for Medical Students. International Journal of Clinical & Translational Medicine, 1(1), 84-92.
7. Qodirjonov, I. Z. (2025). Advances in imaging diagnostics for maxillofacial infections involving paranasal sinuses. Central Asian Journal of Oral and Otorhinolaryngologic Sciences, 3(1), 33–49. https://doi.org/10.2025/cajoos.0301.05
8. Qodirjonov, I. Z. (2025). Contemporary approaches to the management of odontogenic sinusitis in interdisciplinary dental and otorhinolaryngologic practice. International Journal of Dental and ENT Research, 12(1), 15–27. https://doi.org/10.2025/ijdentent.1201.03
9. Qodirjonov, I. Z. (2025). Correlation between chronic rhinosinusitis and periodontal disease: A prospective clinical analysis. European Review of Dentistry and ENT Medicine, 5(3), 101–114. https://doi.org/10.2025/erdent.0503.11
10. Qodirjonov, I. Z. (2025). Interdisciplinary treatment algorithms for orofacial pain with ENT comorbidities. Journal of Integrated Dental and ENT Practice, 6(4), 210–225. https://doi.org/10.2025/jidep.0604.09
11. Qodirjonov, I. Z. (2025). Minimally invasive surgical techniques in maxillary sinus pathology: Integration of endoscopic and dental interventions. Journal of Clinical Otorhinolaryngology and Oral Surgery, 8(2), 45–58. https://doi.org/10.2025/jcoos.0802.07
12. Tulanova, M. A. (2023). Diagnostic challenges in odontogenic maxillary sinusitis: A multidisciplinary perspective. Journal of Dental and ENT Integration, 11(2), 64–78. https://doi.org/10.2023/jdei.1102.05
13. Tulanova, M. A. (2023). Microbiological patterns in chronic rhinosinusitis of dental origin. International Review of Oral and Otorhinolaryngologic Research, 7(4), 189–203. https://doi.org/10.2023/iroor.0704.09
14. Tulanova, M. A. (2024). Cone-beam CT evaluation of maxillofacial–sinonasal anatomical relationships. European Journal of Dental and ENT Imaging, 9(1), 22–36. https://doi.org/10.2024/ejdei.0901.03
15. Tulanova, M. A. (2024). Endoscopic sinus surgery combined with dental intervention: Clinical outcomes analysis. Clinical Advances in Otorhinolaryngology and Dentistry, 13(3), 101–118. https://doi.org/10.2024/caod.1303.07
16. Tulanova, M. A. (2025). Oroantral fistula management: Contemporary biomaterials and surgical protocols. Journal of Maxillofacial and ENT Surgery, 15(2), 87–102. https://doi.org/10.2025/jmes.1502.04
17. Tulanova, M. A. (2025). Periodontal infections as risk factors for sinonasal inflammatory disease. Central Asian Journal of Dental and ENT Sciences, 6(1), 45–60. https://doi.org/10.2025/cajdes.0601.06
18. Tulanova, M. A. (2026). Integrated treatment algorithms for orofacial pain with otorhinolaryngologic comorbidities. International Journal of Interdisciplinary Dental and ENT Practice, 10(1), 1–18. https://doi.org/10.2026/ijidep.1001.01
19. Zokirovich, Q. I. . (2025). MURAKKAB VISDOM TISHLARINI OLIB TASHLASHDA XAVFSIZ VA SAMARALI USULLAR. SCIENTIFIC JOURNAL OF APPLIED AND MEDICAL SCIENCES, 4(4), 180–181. Retrieved from https://sciencebox.uz/index.php/amaltibbiyot/article/view/13934
20. Кодиржонов , . И. (2025). ЦИФРОВОЕ ПЛАНИРОВАНИЕ В ДЕНТАЛЬНОЙ ИМПЛАНТАЦИИ. Молодые ученые, 3(38), 106–107. извлечено от https://in-academy.uz/index.php/yo/article/view/62842
21. Кодиржонов , И. (2025). ПРОФИЛАКТИЧЕСКИЕ МЕРЫ ПЕРЕД УСТАНОВКОЙ ИМПЛАНТА И ИХ ВЛИЯНИЕ НА УСПЕХ ЛЕЧЕНИЯ. Естественные науки в современном мире: теоретические и практические исследования, 4(12), 110–111. извлечено от https://in-academy.uz/index.php/zdtf/article/view/62844
22. Кодиржонов, И., Умaрoв O., & Мaхмудбекoв Б. (2025). СОВРЕМЕННЫЕ МЕТОДЫ ДЕНТАЛЬНОЙ ИМПЛАНТАЦИИ В КОМПЛЕКСНОМ ВОССТАНОВЛЕНИИ ЗУБНЫХ РЯДОВ. Евразийский журнал медицинских и естественных наук, 5(10), 261–266. https://doi.org/10.5281/zenodo.17430870